For decades, little was understood about DIPG/DMG tumors. However, in recent years, researchers have gained the ability to analyze tissue due to the increased safety of brainstem biopsies.
This ability to analyze brain tissue has allowed researchers to gain a better understanding of this disease and make progress toward finding a cure.
DIPG is not known to be hereditary, meaning it is not passed down from parent to child. The genetic mutations that cause DIPG are also not known to be environmentally influenced, meaning there is nothing a parent did or did not do that caused DIPG to occur in their child.
DIPG is a classic example of a developmentally based tumor because it is influenced by particular cells that are present in the highest concentrations while the brain is developing. This theory is supported by the fact that DIPG/DMG most often occurs during middle childhood, a period in which the brain develops significantly.